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Identification of Suitable Amalgamation with Resveratrol, Epigallocatechin-3-gallate, and Diallyl Trisulfide against Skin Cancer Cell Lines (A431) (Record no. 130078)
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| 000 -LEADER | |
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| fixed length control field | 02081nam a2200181 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 241108b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Gobika Arumugam, |
| 245 ## - TITLE STATEMENT | |
| Title | Identification of Suitable Amalgamation with Resveratrol, Epigallocatechin-3-gallate, and Diallyl Trisulfide against Skin Cancer Cell Lines (A431) |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | P178-186 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | Resveratrol, Epigallocatechin -3-gallate (EGCG) and Diallyl Trisulfide (DATS) are bioactive compounds in which two polyphenols and an organosulfur are naturally occurring bioactive chemicals that can be efficacious in skin cancer chemoprevention either independently or in combination. Objectives: Conglomerate analysis of RES, EGCG, and DATS was performed as a single and in binary combinations to investigate cancer cell viability, in vitro in the A431 (human epidermoid carcinoma) skin cancer cell line. Materials and Methods: Screening of cytotoxicity potential of bioactive combinations by MTT assay, nuclear fragmentation: Acridine orange / ethidium bromide AO/EtBr assay on skin cancer cell lines (A431). Results: Our result showed that the half-maximal growth inhibitory concentration for RES-(IC50)-42 µM/mL, EGCG (IC50)-44 µM/mL, and DATS (IC50)-36 µM/mL whereas the binary combination RES + EGCG (IC50)-20 µM/mL; EGCG + DATS (IC50)-13 µM/mL; DATS + RES (IC50)-24 µM/mL which is evident from the uptake of AO and EtBr dyes by live/dead cells. Conclusion: Amalgam of RES, EGCG, and DATS can succor to develop skin cancer treatment better than as a single. Compared to all the combinations EGCG + DATS possess higher anticancer potentials against A431 skin cancer cell line. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href=" Skin cancer"> Skin cancer</a> |
| -- | <a href=" Synergistic effect of Resveratrol"> Synergistic effect of Resveratrol</a> |
| -- | <a href="Epigallocatechin-3-gallate,">Epigallocatechin-3-gallate,</a> |
| -- | <a href=", Diallyl trisulfide, ">, Diallyl trisulfide, </a> |
| -- | <a href=" Dietary bioactive compound."> Dietary bioactive compound.</a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sangilimuthu Alagar Yadav* |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125266 |
| Host Itemnumber | 109601 |
| Place, publisher, and date of publication | Banglore Association of Pharmaceutical Tearchers of India |
| Title | Indian Journal of Pharmaceutical Education and Research |
| International Standard Serial Number | 0019-5464 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| 773 0# - HOST ITEM ENTRY | |
| -- | JP44 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| -- | ddc |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 08/11/2024 | JP44.19 | 08/11/2024 | 08/11/2024 | Journal Article |