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Histopathological and Biochemical Investigation of the Effect of Shepherd's Purse (Capsella bursa-pastoris L.) on Ethanol-Induced Liver Damage (Record no. 130083)
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| 000 -LEADER | |
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| fixed length control field | 01834nam a2200181 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 241108b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Orhan Polat1 |
| 245 ## - TITLE STATEMENT | |
| Title | Histopathological and Biochemical Investigation of the Effect of Shepherd's Purse (Capsella bursa-pastoris L.) on Ethanol-Induced Liver Damage |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | p198-203 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | The aim of the present study was to investigate the hepatoprotective effect of Shepherd's Purse (SP) herbal tea on ethanol (EtOH)-induced liver toxicity. Materials and Methods: Male Wistar rats (n = 32) were divided into 4 experimental groups: control, EtOH (30% EtOH), EtOH+SP (30% EtOH+1 mL/kg SP), and SP (1 mL/kg SP orally). EtOH and SP were administered by orogastric gavage once daily. At the end of the 60-day experimental period, tissue and blood samples were obtained from the rats following necropsy. Results: Histopathologically, degenerative-necrotic changes in the liver of the EtOH group rats were partially reduced in the SP treatment group. Biochemical examinations revealed that SP treatment decreased aspartic transaminase, alanine transaminase, and alkaline phosphatase levels in the SP-treated rats compared to the EtOH group rats. While SP treatment had a positive effect on the triglyceride and HDL levels, it had a negative effect on the LDL and cholesterol levels. Conclusion: Consequently, it was determined that SP tea provides partial protection against EtOH-induced liver toxicity. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href=": Shepherd's purse">: Shepherd's purse</a> |
| -- | <a href="Ethanol, Histopathology">Ethanol, Histopathology</a> |
| -- | <a href=", Liver, Rat.">, Liver, Rat.</a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Turan Yaman2 |
| -- | Ahmet Ufuk Kömüroğlu3 |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125266 |
| Host Itemnumber | 109601 |
| Place, publisher, and date of publication | Banglore Association of Pharmaceutical Tearchers of India |
| Title | Indian Journal of Pharmaceutical Education and Research |
| International Standard Serial Number | 0019-5464 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| 773 0# - HOST ITEM ENTRY | |
| -- | JP44 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| -- | ddc |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
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| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 08/11/2024 | jp44.21 | 08/11/2024 | 08/11/2024 | Journal Article | |||||
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 11/11/2024 | JP44.23 | 11/11/2024 | 11/11/2024 | Journal Article |