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Risk of Respiratory Diseases with Use of Psychotropic Drugs: Results of a Community-based Cross-sectional Study from South India (Record no. 130120)
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| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Abhirami Eby |
| 245 ## - TITLE STATEMENT | |
| Title | Risk of Respiratory Diseases with Use of Psychotropic Drugs: Results of a Community-based Cross-sectional Study from South India |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | P-333-341 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | The study evaluated the effect of various psychotropics on pulmonary function to identify the psychotropic drug class most commonly associated with risk of respiratory disorders. Since psychotropic medications have safety concerns for usage in general population, their use in people with Coronavirus Disease (COVID-19) is considered challenging. The study may also serve to draw evidence-based practical recommendations for the treatment of people with COVID-19. Materials and Methods: A 10-item containing questionnaire was designed to capture clinical information regarding psychotropic use and respiratory disorders. Internal consistency and reproducibility were determined using Cronbach’s alpha and intra-class correlation coefficient respectively. A validated questionnaire was administered to patients or caregivers at a community pharmacy setup and data was collected through electronic data capture. All captured data were summarized descriptively and statistically analyzed using R Studio 4.0. Results: Cronbach’s alpha and intra-class correlation coefficient values were found to be 0.92 and 0.85 respectively. In a sample of 198 patients, benzodiazepines were the commonly used medication (43.9%) followed by selective serotonin reuptake inhibitors (21.2%), anti-psychotics (15.1%), mood stabilizers (7.6%) and others (12.2%). A statistically significant association was observed between benzodiazepine, second-generation antipsychotics, and respiratory disorders (OR 1.56 [1.1 – 2.3, p<0.1]). However, the use of first-generation antipsychotics was found to be less associated with respiratory infections. Conclusion: Benzodiazepine and second-generation antipsychotics were found to be significantly associated with respiratory disorders. Hence patients on psychotropics should be monitored for respiratory symptoms and the choice of anti-psychotic medications should be on existing clinical evidence. The psychotropics which were found to be safer through the study can be chosen to improve the quality of psychiatric care in COVID-19 patients, also promoting an optimal management of psychiatric conditions without worsening the medical condition due to COVID-19. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Psychotropic">Psychotropic</a> |
| -- | <a href=" Antipsychotics"> Antipsychotics</a> |
| -- | <a href=" Respiratory disorder"> Respiratory disorder</a> |
| -- | <a href=" Pneumonia"> Pneumonia</a> |
| -- | <a href=" COVID-19."> COVID-19.</a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Raman Dang, |
| -- | Elsa Jacob |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125266 |
| Host Itemnumber | 109601 |
| Place, publisher, and date of publication | Banglore Association of Pharmaceutical Tearchers of India |
| Title | Indian Journal of Pharmaceutical Education and Research |
| International Standard Serial Number | 0019-5464 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| 773 0# - HOST ITEM ENTRY | |
| -- | JP44 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| -- | ddc |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
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| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 11/11/2024 | JP44.35 | 11/11/2024 | 11/11/2024 | Journal Article |