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SYNTHESIS AND IN VIVO EVALUATION OF SOME NEW PYRAZOL INDOLES, THEIR AZO AND MANNICH SALTS AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS (Record no. 130734)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01411nam a2200181 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250114b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Archana |
| 245 ## - TITLE STATEMENT | |
| Title | SYNTHESIS AND IN VIVO EVALUATION OF SOME NEW PYRAZOL INDOLES, THEIR AZO AND MANNICH SALTS AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | P. 21-28 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | This paper deals with the design, synthesis and biological evaluation of new pyrazolyl indole derivatives including azo compounds and Mannich salts. The work of this research could lead to potentially useful analgesic and anti-inflammatory agents. Utilizing the synthetic route illustrated in Fig. 1, compounds 1 to 30 have been synthesized. All synthesized compounds have been characterized using TLC, elemental analysis for C, H and N and spectral methods involving IR, 1H-NMR, and mass spectroscopy. All tests conducted on standard models in vivo have exhibited excellent analgesic and anti-inflammatory activity, thus suggesting potential therapeutic applications. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Pyrazolyl indoles ">Pyrazolyl indoles </a> |
| -- | <a href="azo compounds ">azo compounds </a> |
| -- | <a href="Mannich salts ">Mannich salts </a> |
| -- | <a href="spectral studies ">spectral studies </a> |
| -- | <a href="analgesic agents ">analgesic agents </a> |
| -- | <a href="anti-inflammatory agents ">anti-inflammatory agents </a> |
| -- | <a href="acute toxicity ">acute toxicity </a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Meenakshi Yadav |
| -- | Sakshi Chaudhary |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125265 |
| Host Itemnumber | 111177 |
| Place, publisher, and date of publication | Mumbai Indian Drugs Manufacturer's Association |
| Title | Indian Drugs |
| International Standard Serial Number | 0019-462X |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| 773 0# - HOST ITEM ENTRY | |
| -- | JP490 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| -- | ddc |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 14/01/2025 | JP490.2 | 14/01/2025 | 14/01/2025 | Journal Article |