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ASSESSMENT OF BLOOD GLUCOSE LEVELS IN WISTAR RATS TREATED WITH COCCINIA GRANDIS AND DATA INTERPRETATION BASED ON NON-COMPARTMENT ANALYSIS AND RATE PROCESS (Record no. 130739)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01703nam a2200181 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250114b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Betsy Sunny |
| 245 ## - TITLE STATEMENT | |
| Title | ASSESSMENT OF BLOOD GLUCOSE LEVELS IN WISTAR RATS TREATED WITH COCCINIA GRANDIS AND DATA INTERPRETATION BASED ON NON-COMPARTMENT ANALYSIS AND RATE PROCESS |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | P.63-75 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | The study aims to examine the blood glucose-lowering effects of fresh Coccinia grandis fruit and assess how drying affects its antidiabetic potential. Additionally, the study seeks to determine the optimal administration procedure to maximize its antidiabetic efficacy. An oral glucose tolerance test was performed in female Albino Wistar rats to study the effects of C. grandis in three forms: fresh fruit slurry, dry fruit powder, and overnight soaked dry powder, with metformin as standard. The fresh fruit slurry (S-1) of C. grandis demonstrates excellent antidiabetic properties, showing a mean blood glucose level of 116.25±38 and a percentage blood glucose reduction of about 30%. This is more effective compared to the processed form of C. grandis and the standard drug metformin, with a mean actual blood glucose level of 44.5±35.9. The study indicates that C. grandis fresh form possesses significant hypoglycemic effects, reducing glucose absorption by peripheral tissues and enhancing glucose uptake into cells. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Blood glucose level">Blood glucose level</a> |
| -- | <a href="C.grandis ">C.grandis </a> |
| -- | <a href="oral glucose tolerance test ">oral glucose tolerance test </a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dhanish Joseph |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125265 |
| Host Itemnumber | 111177 |
| Place, publisher, and date of publication | Mumbai Indian Drugs Manufacturer's Association |
| Title | Indian Drugs |
| International Standard Serial Number | 0019-462X |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| 773 0# - HOST ITEM ENTRY | |
| -- | JP490 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| -- | ddc |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 14/01/2025 | JP490.5 | 14/01/2025 | 14/01/2025 | Journal Article | |||||
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 14/01/2025 | JP490.6 | 14/01/2025 | 14/01/2025 | Journal Article |