SNDT WOMEN'S UNIVERSITY
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Santacruz (West) Mumbai - 400049
Huei-Rong Guo (Record no. 130887)
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| 000 -LEADER | |
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| fixed length control field | 02222nam a2200169 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250203b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Novel food isolates with striking α-glucosidase inhibitory activity and probiotic potential for an antidiabetic role |
| 245 ## - TITLE STATEMENT | |
| Title | Huei-Rong Guo |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | p-1283-1294 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | In the current study, ten lactic acid bacteria (LAB) isolates exhibiting anti-α-glucosidase activity were isolated from fermented food. It is directed at novel supplementary diets to prevent/improve diet-induced carbohydrate metabolism disorders and related chronic diseases. Moreover, to evaluate their safety, functionality, and probiotic potential via in vitro simulated test conditions. From 16s-rRNA sequencing, Pediococcus acidilactici (NKUST 803, 845, 858), Lactobacillus plantarum (NKUST 817, 828, 851), Levilactobacillus brevis (NKUST 816, 855) and Lactobacillus acidophilus (NKUST 803, 863) were identified. The results showed that the isolates possessed anti-pathogenic activity, auto-aggregation ability, hydrophobicity (47.44–96.4%), and gastric acid-resistant activity (79–99.1%), which proved their potential for probiotics in nutraceuticals to render hypoglycemic activity or antidiabetic effects to the host positively. Among tested isolates, L. plantarum 817 and P. acidilactici 858 exhibited maximum α-glucosidase inhibitory (AGI) activity of 35–40%. The heat map clearly showed that L. plantarum 817 exhibited the best AGI activity and probiotic potential, among others. These were studied under various simulated gut conditions and safety tests. However, all isolates possess the potential to be used as probiotics in commercial-scale health applications. Pediococcus sp. possesses notable AGI activity but relatively less colonization potential in the gut hence recommended daily intake for positive health effects. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="α-glucosidase inhibitory activity Probiotic Lactobacillus Hypoglycemic effect Diabetes">α-glucosidase inhibitory activity Probiotic Lactobacillus Hypoglycemic effect Diabetes</a> |
| -- | <a href="Probiotic ">Probiotic </a> |
| -- | <a href="Lactobacillus ">Lactobacillus </a> |
| -- | <a href="Hypoglycemic effect ">Hypoglycemic effect </a> |
| -- | <a href="Diabetes">Diabetes</a> |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 80310 |
| Host Itemnumber | 109866 |
| Place, publisher, and date of publication | Germany Springer |
| Title | Journal of Food Science and Technology |
| International Standard Serial Number | 0022-1155 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| 773 0# - HOST ITEM ENTRY | |
| -- | JP261 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| -- | ddc |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 03/02/2025 | JP261.5 | 03/02/2025 | 03/02/2025 | Journal Article |