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FORMULATION AND EVALUATION OF TOPICAL ANTIMICROBIAL EMBELIN NIOSOMAL CREAM (Record no. 131124)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01637nam a2200157 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250214b |||||||| |||| 00| 0 eng d |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Item number | P.34-39 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Kritika R. Saboo |
| 245 ## - TITLE STATEMENT | |
| Title | FORMULATION AND EVALUATION OF TOPICAL ANTIMICROBIAL EMBELIN NIOSOMAL CREAM |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | P.34-39 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | Embelin, isolated from Embelia ribes berries is a major constituent isolated by the Soxhlet process and possesses antimicrobial activity. In this report, we develop and evaluate the topical antimicrobial embelin niosomal cream formulation. Niosomal formulation of embelin was formulated using a thin-film hydration method using Tween™ 60, chloroform and phosphate buffer with a rotary evaporator. This niosomal formulation was incorporated into the cream base, where both oil and water phase ingredients were prepared separately at 70 o C by constant stirring to form w/o (water-in-oil) cream formulation. This niosomal cream was evaluated for particle size, entrapment efficacy, spreadability, centrifugation, viscosity, dye test, homogeneity, in vitro antifungal and antibacterial activity against C. albicans and S. aureus, respectively. The zone of inhibition was calculated and further compared with the market formulations. The study proposed that niosomal formulations delivered sustained and prolonged delivery of drug with increase in bioavailability. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Embelin">Embelin</a> |
| -- | <a href="niosome">niosome</a> |
| -- | <a href="thin-film hydration">thin-film hydration</a> |
| -- | <a href="entrapment efficacy ">entrapment efficacy </a> |
| -- | <a href="antimicrobial tests ">antimicrobial tests </a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rohit R. Ghadgea |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125265 |
| Host Itemnumber | 109909 |
| Place, publisher, and date of publication | Mumbai Indian Drugs Manufacturer's Association |
| Title | Indian Drugs |
| International Standard Serial Number | 0019-462X |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Koha normalized classification for sorting | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Koha full call number | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
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| Dewey Decimal Classification | P__3439 | SNDT Juhu | SNDT Juhu | 14/02/2025 | P.34-39 | JP288.3 | 14/02/2025 | 14/02/2025 | Journal Article |