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FORMULATION AND EVALUATION OF NANOSTRUCTURED LIPID CARRIERS BASED CAPSULE (Record no. 131126)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01418nam a2200157 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250214b |||||||| |||| 00| 0 eng d |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Item number | P.49-58 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Karan K. Lokhande |
| 245 ## - TITLE STATEMENT | |
| Title | FORMULATION AND EVALUATION OF NANOSTRUCTURED LIPID CARRIERS BASED CAPSULE |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | P.49-58 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | The objective of this investigation was to formulate an ideal nanostructured lipid carrier (NLC) for glibenclamide in oral capsules. Employing factorial design, the NLC formulation was achieved through high-pressure homogenization using Design-Expert® software, optimized using a 32 -factor experimental design and response surface analysis. Comprehensive analyses were conducted to characterize NLCs and determine the optimal formulation. Rigorous evaluations, including drug content, in vitro diffusion and stability studies, were performed. Safety assessments, efficacy studies and optimization led to the identification of an optimal NLC formulation with specific lipid and surfactant percentages, resulting in a desirable particle size (nm) and a robust zeta potential indicative of strong physical stability. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Nanostructured lipid carriers ">Nanostructured lipid carriers </a> |
| -- | <a href="glibenclamide ">glibenclamide </a> |
| -- | <a href="lipid nanoparticles ">lipid nanoparticles </a> |
| -- | <a href="capsule ">capsule </a> |
| -- | <a href="diabetes">diabetes</a> |
| -- | <a href="factorial design ">factorial design </a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pranali P. Malusare |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125265 |
| Host Itemnumber | 109909 |
| Place, publisher, and date of publication | Mumbai Indian Drugs Manufacturer's Association |
| Title | Indian Drugs |
| International Standard Serial Number | 0019-462X |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Koha normalized classification for sorting | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Koha full call number | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | P__4958 | SNDT Juhu | SNDT Juhu | 14/02/2025 | P.49-58 | JP288.5 | 14/02/2025 | 14/02/2025 | Journal Article |