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BIO-PROSPECTING FOR ACTIVE COMPOUNDS: FTIR AND GCMS PROFILING OF ETHYL ACETATE-EXTRACTED SECONDARY METABOLITES FROM SEA WATER-ORIGIN ACINETOBACTER BAUMANNII MP-1 (Record no. 131143)

MARC details
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fixed length control field 02461nam a2200157 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Item number P.59-68
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Jeyameenakshi Annamalai
245 ## - TITLE STATEMENT
Title BIO-PROSPECTING FOR ACTIVE COMPOUNDS: FTIR AND GCMS PROFILING OF ETHYL ACETATE-EXTRACTED SECONDARY METABOLITES FROM SEA WATER-ORIGIN ACINETOBACTER BAUMANNII MP-1
300 ## - PHYSICAL DESCRIPTION
Extent P.59-68
520 ## - SUMMARY, ETC.
Summary, etc. biblio.abstract It is alarming and concerning that, as time progresses, due to lifestyle modifications and the emergence of resistant microbial strains, the need to explore novel drugs against them is escalating and becoming a trend. Natural products are versatile substances with remarkable qualities that could be manipulated to reap beneficial outcomes, if managed rigorously. Among the natural troves, the marine environment is one of the most jubilant environments as it harbors diverse ecosystems where organisms adapt various mechanisms and possess many complex molecules to tackle the harsh conditions around them. Bacteria are an omnipresent entity, and it has been proven previously that the bacteria from marine environments can produce secondary metabolites or marine natural products with many crucial biological applications. This study investigated the bioactive compounds present in the secondary metabolite (ethyl acetate extracted crude- EAEC) extracted from the antagonistic bacteria Acinetobacter baumannii (MP-1) isolated from seawater; concurrently, it also explored the possible pharmaceutical applications of the EAEC. FTIR analysis showed the presence of variety of functional groups and GC-MS spectroscopy unraveled the existence of a wide range of bioactive compounds, including the derivatives of oxazine, pentanoic acid, butanoic acid, dehydromevalonic lactone, etc. The identified compounds from the EAEC have all been previously recorded for their valuable (antibacterial, anticancer, antimalarial, and herbicidal) biological activities. It could be suggested that the EAEC from antagonistic bacterial strain MP-1 can be utilized as a drug after ascertaining its potential through further in vivo and in vitro trials.
654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS
Subject <a href="Secondary metabolites ">Secondary metabolites </a>
-- <a href="marine natural products ">marine natural products </a>
-- <a href="bioactive compounds ">bioactive compounds </a>
-- <a href="functional compounds ">functional compounds </a>
-- <a href="qualitative profiling ">qualitative profiling </a>
-- <a href="antagonistic bacteria ">antagonistic bacteria </a>
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Harini Kasilingam
773 0# - HOST ITEM ENTRY
Host Biblionumber 125265
Host Itemnumber 109909
Place, publisher, and date of publication Mumbai Indian Drugs Manufacturer's Association
Title Indian Drugs
International Standard Serial Number 0019-462X
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Koha normalized classification for sorting Not for loan Location (home branch) Sublocation or collection (holding branch) Date acquired Koha issues (times borrowed) Koha full call number Piece designation (barcode) Koha date last seen Price effective from Koha item type
    Dewey Decimal Classification   P__5968   SNDT Juhu SNDT Juhu 15/02/2025   P.59-68 JP288.6 15/02/2025 15/02/2025 Journal Article