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SAFETY ASSESSMENT OF AYURVEDIC GOLD MEDICATION SUVARNA BHASMA, IN WISTAR RATS (Record no. 131178)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01516nam a2200157 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250220b |||||||| |||| 00| 0 eng d |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Item number | P.65-71 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Abhay N. Kulkarni |
| 245 ## - TITLE STATEMENT | |
| Title | SAFETY ASSESSMENT OF AYURVEDIC GOLD MEDICATION SUVARNA BHASMA, IN WISTAR RATS |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | P.65-71 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | Suvarna bhasma (SB) contains gold and lead, which are highly potent metals and are toxic in their crude form. This study evaluated the safety profile of the medication. Suvarna bhasma was administered for 90 consecutive days orally at three doses (10.23 mg kg-1, 40.92 mg kg-1 and 102.3 mg kg-1 body weight) to wistar rats. Clinical observations, feed and water consumption, and body weight changes were noted during the study period. On the 91st day, hematological, biochemical and histopathological changes were studied. There was a significant decrease in body weight of rats at a low dose (10.23 mg kg-1) at fourth week, which could not be correlated with feed and water consumption findings. Thus, change was not considered as a treatment-related effect. Suvarna bhasma showed no evident untoward effect in haematological, biochemical and histopathological parameters in the 90 day-subchronic toxicity study (OECD 408 guidelines) and was safe in Wistar rats. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Suvarna bhasma ">Suvarna bhasma </a> |
| -- | <a href="toxicity">toxicity</a> |
| -- | <a href="herbo-metallic ">herbo-metallic </a> |
| -- | <a href="heavy metals ">heavy metals </a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahalaxmi Mohan |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125265 |
| Host Itemnumber | 109669 |
| Place, publisher, and date of publication | Mumbai Indian Drugs Manufacturer's Association |
| Title | Indian Drugs |
| International Standard Serial Number | 0019-462X |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Koha normalized classification for sorting | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Koha full call number | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | P__6571 | SNDT Juhu | SNDT Juhu | 20/02/2025 | P.65-71 | JP113.6 | 20/02/2025 | 20/02/2025 | Journal Article |