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IN VITRO ANTIOBESITY ACTIVITY OF SOME PLANTS THROUGH A MODIFIED LIPASE INHIBITION ASSAY (Record no. 131179)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01823nam a2200157 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250220b |||||||| |||| 00| 0 eng d |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Item number | P.72-75 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Radheshyam |
| 245 ## - TITLE STATEMENT | |
| Title | IN VITRO ANTIOBESITY ACTIVITY OF SOME PLANTS THROUGH A MODIFIED LIPASE INHIBITION ASSAY |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | P.72-75 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | The objective of the present study was to evaluate the antiobesity potential of various plant (leaves or seed) extracts through a modified in vitro lipase inhibitory activity assay. Dimethyl sulphoxide (DMSO, negative control or solvent) extracts as cold infusion of leaves and seeds of some plants were studied for lipase inhibitory potential using porcine pancreatic lipase enzyme, p- nitro phenyl acetate and orlistat (as positive control or standard inhibitor). Among the leaves, the Urtica dioica showed the best pancreatic lipase inhibition activity (52.0 %). On the other hand, among the seeds, Trachyspermum ammi showed the highest per cent lipase inhibition (91.68 %). Among six leaves’ and seven seeds’ extract, it was evident that the seeds showed better pancreatic lipase inhibition activity over the leaves in the study. The lipase inhibition was found to be in the range of 34.43 to 91.68 % for the plants in study. DMSO extract of the plants under the study showed significant pancreatic lipase inhibitory activity indicating strong antiobesity activity. Therefore, the plants can be further investigated for the identification and isolation of chief bioactive constituents for developing the lead molecules for obesity treatment. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Obesity ">Obesity </a> |
| -- | <a href="antiobesity ">antiobesity </a> |
| -- | <a href="lipase inhibition ">lipase inhibition </a> |
| -- | <a href="herbal drugs ">herbal drugs </a> |
| -- | <a href="weight management ">weight management </a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bhawna Basnal |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125265 |
| Host Itemnumber | 109669 |
| Place, publisher, and date of publication | Mumbai Indian Drugs Manufacturer's Association |
| Title | Indian Drugs |
| International Standard Serial Number | 0019-462X |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Koha normalized classification for sorting | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Koha full call number | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | P__7275 | SNDT Juhu | SNDT Juhu | 20/02/2025 | P.72-75 | JP113.7 | 20/02/2025 | 20/02/2025 | Journal Article |