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FORMULATION AND EVALUATION OF β-SITOSTEROL LOADED NIOSOMES FOR ENHANCED ANTIDIABETIC ACTIVITY: A POTENTIAL ALTERNATIVE IN TYPE 2 DIABETES MANAGEMENT (Record no. 131183)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01430nam a2200157 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250221b |||||||| |||| 00| 0 eng d |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Item number | P.45-51 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Priya Tiwari |
| 245 ## - TITLE STATEMENT | |
| Title | FORMULATION AND EVALUATION OF β-SITOSTEROL LOADED NIOSOMES FOR ENHANCED ANTIDIABETIC ACTIVITY: A POTENTIAL ALTERNATIVE IN TYPE 2 DIABETES MANAGEMENT |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | P.45-51 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | Niosomes, vesicles formed by non-ionic surfactants, offer advantages in drug delivery by enhancing solubilization and encapsulating both lipophilic and hydrophilic drugs. This study focuses on β-sitosterol-loaded niosomes designed to protect its anti-diabetic properties. Formulated with Span™ 60, Span™ 80 and cholesterol, the niosomes showed high entrapment efficiency (90%) and favorable release kinetics. Stability studies confirmed their robustness in various conditions. In vivo experiments demonstrated significant improvements in body weight and blood glucose levels in diabetic rats. The optimized formulation (NF8) exhibited controlled release and substantial antidiabetic activity, suggesting its potential as an effective treatment for type 2 diabetes mellitus. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Niosomes ">Niosomes </a> |
| -- | <a href="non-ionic surfactants">non-ionic surfactants</a> |
| -- | <a href="B-sitosterol ">B-sitosterol </a> |
| -- | <a href="release kinetics ">release kinetics </a> |
| -- | <a href="blood glucose level ">blood glucose level </a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rajat Srivastava |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125265 |
| Host Itemnumber | 109707 |
| Place, publisher, and date of publication | Mumbai Indian Drugs Manufacturer's Association |
| Title | Indian Drugs |
| International Standard Serial Number | 0019-462X |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Koha normalized classification for sorting | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Koha full call number | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | P__4551 | SNDT Juhu | SNDT Juhu | 21/02/2025 | P.45-51 | JP151.4 | 21/02/2025 | 21/02/2025 | Journal Article |