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Berberine’s Therapeutic Prospects in Parkinson’s Disease: A Spotlight on Cholesterol Regulation for Cognitive Improvement (Record no. 131237)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01169nam a2200121 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250228b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | T Lakshmi Narayanan, |
| 245 ## - TITLE STATEMENT | |
| Title | Berberine’s Therapeutic Prospects in Parkinson’s Disease: A Spotlight on Cholesterol Regulation for Cognitive Improvement |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | Cholesterol synthesized in astrocytes of the cerebrum plays a pivotal role in regulating hippocampal neurogenesis and cognitive function. Dysregulation of cholesterol metabolism has emerged as a key contributor to the pathogenesis of Parkinson’s disease. Elevated cholesterol levels in the brain are associated with increased oxidative stress and subsequent neurodegeneration of hippocampal pyramidal neurons, culminating in cognitive impairment. Berberine, an isoquinoline alkaloid has the potential to modulate cholesterol synthesis through HMG-CoA inhibition. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Parkinson’s Disease, ">Parkinson’s Disease, </a> |
| -- | <a href="Cognitive impairment,">Cognitive impairment,</a> |
| -- | <a href=" Dopamine"> Dopamine</a> |
| -- | <a href=", Cholesterol,">, Cholesterol,</a> |
| -- | <a href=" Alpha-synuclein,"> Alpha-synuclein,</a> |
| -- | <a href=" Berberine"> Berberine</a> |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125266 |
| Host Itemnumber | 111205 |
| Place, publisher, and date of publication | Banglore Association of Pharmaceutical Tearchers of India |
| Title | Indian Journal of Pharmaceutical Education and Research |
| International Standard Serial Number | 0019-5464 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 28/02/2025 | JP502.9 | 28/02/2025 | 28/02/2025 | Journal Article |