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Essential oils from Conamomum rubidum: The phytochemical, microbiological, and molecular docking study (Record no. 131242)
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| 000 -LEADER | |
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| fixed length control field | 02125nam a2200145 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250228b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Nguyen Thanh Tung |
| 245 ## - TITLE STATEMENT | |
| Title | Essential oils from Conamomum rubidum: The phytochemical, microbiological, and molecular docking study |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | P.391-401 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | This study explored the interaction of major components in essential oils from aerial parts and rhizomes of Conamomum rubidum (Lamxay & N.S.Lý) Škorničk. & A.D. Poulsen (Zingiberaceae) collected in Hongiao National Park (Lamdong province, Vietnam) to the relevant targets of microtubes. Δ-3-Carene (33.14% and 20.15%), β-phellandrene (14.63% and 25.61%), and 1,8-cineole (17.14 and 3.26%) were three major components in essential oils from aerial parts and rhizome of C. rubidum, respectively. The aerial parts oil possessed fungicidal activity against Candida albicans (MIC = MFC = 0.4%) and rhizome oil bactericidal activity against Staphylococcus aureus (MIC = MBC = 0.8%). A molecular docking study was performed with antimicrobial targets of S. aureus (2W9S, 1HSK, 2ZCQ) and C. albicans (3PVK, 5V5Z, 1IYL). Among the three components, β-phellandrene has the best affinity to the relevant targets of S. aureus, while Δ-3-care and 1,8-cineole exhibited good binding energy to the targets of C. albicans compared to β-phellandrene. Along with the in vitro activity test, the docking study demonstrated that β-phellandrene kept an important role in the ability to inhibit S. aureus. At the same time, Δ-3-carene and 1,8-cineole played a significant part in the capacity to inhibit C. albicans. By the ADMET calculations, Δ-3-carene, β-phellandrene, and 1,8-cineole can potentially be used as antimicrobial agents. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Antimicrobial activity">Antimicrobial activity</a> |
| -- | <a href="Candida albicans">Candida albicans</a> |
| -- | <a href="Conamomum rubidum">Conamomum rubidum</a> |
| -- | <a href="Essential oil">Essential oil</a> |
| -- | <a href="Molecular docking">Molecular docking</a> |
| -- | <a href="Staphylococcus aureus">Staphylococcus aureus</a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nguyen Khac Tiep |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125285 |
| Host Itemnumber | 110651 |
| Place, publisher, and date of publication | New Delhi NISCAIR |
| Title | Indian Journal of Natural Products and Resources |
| International Standard Serial Number | 0976-0504 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
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| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 28/02/2025 | JP363.5 | 28/02/2025 | 28/02/2025 | Journal Article |