SNDT WOMEN'S UNIVERSITY
BMK Knowledge Resource Centre
Vithaldas Vidyavihar, Juhu Tara Road,
Santacruz (West) Mumbai - 400049
Phytochemical profiles and cytotoxicity evaluation of the ethanolic extract of Malpighia emarginataleaves: Potential for its therapeutic use (Record no. 131259)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 01944nam a2200145 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250303b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Renato Constantino dos Santos Souza |
| 245 ## - TITLE STATEMENT | |
| Title | Phytochemical profiles and cytotoxicity evaluation of the ethanolic extract of Malpighia emarginataleaves: Potential for its therapeutic use |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | P.294-301 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | The search for new natural compounds with relevant therapeutic properties has increased in recent years. The objective of this study was to investigate the biological properties of the ethanolic extract of Malpighia emarginataleaves. For this, phytochemical assays, high-performance thin layer chromatography (HPTLC), high-performance liquid chromatography (HPLC), antioxidant activity analysis using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and cytotoxicity by hemolysis, and chorioallantoic membrane (CAM) studies were performed. Through qualitative analyses, phenolic compounds and alkaloids were identified, and by quantitative analyses, 92.52, 2.02, and 0.59 μg/mL were found for total flavonoids, total alkaloids, and total phenols, respectively. HPTLC showed the presence of the flavonoids catechin and gallic acid, while HPLC identified myricetin and quercetin. The extract showed a high antioxidant capacity of 80.77% by DPPH. Moreover, low cytotoxicity of the extract at 10% was observed by hemolysis and CAM assay. Our results indicate that the ethanolic extract of M. emarginataleaves is a potential candidate for therapeutic use due to the presence of important bioactive compounds, high antioxidant activity and low cytotoxicity. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Acerola">Acerola</a> |
| -- | <a href=" Alcoholic extract,"> Alcoholic extract,</a> |
| -- | <a href="DPPH">DPPH</a> |
| -- | <a href="HPLC">HPLC</a> |
| -- | <a href="HPTLC,">HPTLC,</a> |
| -- | <a href="hytochemical compounds">hytochemical compounds</a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rodrigo Augusto Cristóvão Ferreira |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125285 |
| Host Itemnumber | 109968 |
| Place, publisher, and date of publication | New Delhi NISCAIR |
| Title | Indian Journal of Natural Products and Resources |
| International Standard Serial Number | 0976-0504 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 03/03/2025 | JP302.8 | 03/03/2025 | 03/03/2025 | Journal Article |