SNDT WOMEN'S UNIVERSITY
BMK Knowledge Resource Centre
Vithaldas Vidyavihar, Juhu Tara Road,
Santacruz (West) Mumbai - 400049
Dynamic protective potential of Couroupitaguianensis Aubl. against reactive free radicals: An approach of simulated in vitro model (Record no. 131452)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02046nam a2200145 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250320b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Kavitha D |
| 245 ## - TITLE STATEMENT | |
| Title | Dynamic protective potential of Couroupitaguianensis Aubl. against reactive free radicals: An approach of simulated in vitro model |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | p. 441-451 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | Oxygen is a prominent element in the well-being of humans, but also responsible for causing tissue damage. The oxygen molecule gets reduced to form a highly reactive oxygen species due to various metabolic events happening in the host. The generated free radicals could react with other biomolecules like protein, lipid, carbohydrate and nucleic acid to impart severediseases and disorders. Antioxidants could effectively block the oxidation process by neutralizing the produced free radicals. Hence, the present study aims to validate the potent antioxidant activities of Couroupita guianensis Aubl. using goat liver slices that could serve as an in vivo simulated in vitro model. The methanolic extract and the alkaloid fraction of both leaves and flowers of C. guianensis Aubl. were prepared and their enzymatic and non-enzymatic antioxidant activities were evaluated. Hydrogen peroxide was used as a standard free radical throughout the experiments in all the treatment groups. The results have envisaged that the plant has enormous antioxidant activities in oxidatively stressed goat liver slices to combat various oxidative stress-related diseases and disorders. Conclusively, the in vitro model system to explore the antioxidant profiles will eventually mitigate the sacrifice of animals by exactly mimicking the in vivo conditions for research endeavors |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Antioxidant ">Antioxidant </a> |
| -- | <a href="Couroupita guianensis Aubl">Couroupita guianensis Aubl</a> |
| -- | <a href="Free radicals">Free radicals</a> |
| -- | <a href="Goat liver slices">Goat liver slices</a> |
| -- | <a href="In vitro mode">In vitro mode</a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Madhumitha M |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125286 |
| Host Itemnumber | 109709 |
| Place, publisher, and date of publication | New Delhi NISCAIR |
| Title | Indian Journal of Traditional Knowledge |
| International Standard Serial Number | 0972-5938 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 20/03/2025 | JP152.6 | 20/03/2025 | 20/03/2025 | Journal Article |