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NOVEL MANGIFERIN-INFUSED PHYTOSOMAL GEL FOR WOUND HEALING: DEVELOPMENT, CHARACTERIZATION AND IN VIVO ASSESSMENT (Record no. 131739)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01551nam a22001337a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250623b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Someshwar D. Mankara |
| 245 ## - TITLE STATEMENT | |
| Title | NOVEL MANGIFERIN-INFUSED PHYTOSOMAL GEL FOR WOUND HEALING: DEVELOPMENT, CHARACTERIZATION AND IN VIVO ASSESSMENT |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | p 35-47 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | Wound healing impairment remains a significant healthcare challenge. This study aimed to develop and evaluate a mangiferin-enriched phytosomal gel formulation to enhance wound healing through improved bioavailability and controlled release. The gel was developed using factorial design with varying concentrations of polymers and characterized through spectroscopic, thermal and microscopic analyses. The optimized formulation showed a particle size of 171.2 nm with high stability and drug entrapment of 87.35%. The gel maintained consistent drug release over 10 h, reaching 93.04% release, and remained stable for six months under accelerated conditions. Animal studies demonstrated superior wound healing efficacy, achieving 97.43% wound contraction after 14 days, compared to 48.21% in the control group. The findings indicate that the mangiferin-enriched phytosomal gel offers an effective solution for enhanced wound healing through improved bioavailability and controlled release properties. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Mangiferin ">Mangiferin </a> |
| -- | <a href="phytosomal gel">phytosomal gel</a> |
| -- | <a href="DSC">DSC</a> |
| -- | <a href="phytosomes">phytosomes</a> |
| -- | <a href="wound healing ">wound healing </a> |
| -- | <a href="optimization">optimization</a> |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125265 |
| Host Itemnumber | 112316 |
| Place, publisher, and date of publication | Mumbai Indian Drugs Manufacturer's Association |
| Title | Indian Drugs |
| International Standard Serial Number | 0019-462X |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 23/06/2025 | JP599.4 | 23/06/2025 | 23/06/2025 | Journal Article |