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ECO-FRIENDLY GREEN SOLVENT UV-SPECTROSCOPIC ANALYTICAL METHOD FOR ETRAVIRINE IN BULK DRUG AND DOSAGE FORM (Record no. 131743)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01379nam a2200133 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250623b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Rajesh S. Chandrabose |
| 245 ## - TITLE STATEMENT | |
| Title | ECO-FRIENDLY GREEN SOLVENT UV-SPECTROSCOPIC ANALYTICAL METHOD FOR ETRAVIRINE IN BULK DRUG AND DOSAGE FORM |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | P 58-66 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | A novel, green analytical method based on UV spectrophotometry has been developed for the practically water-insoluble antiviral drug etravirine in bulk and formulation. The method was validated for multiple parameters like linearity and range, precision, specificity, accuracy and robustness, as per ICH guidelines. The etravirine dissolved in 2 mM benzoic acid in 1 % w/V sodium lauryl sulphate was analyzed at 310 nm. The method demonstrated linearity in the 2.08- 14.56 μg mL-1 range with a correlation coefficient (r2 ) of 0.9997. The method accuracy was in the 100.73 to 101.88 % range. The method is green, eco-friendly, easy, specific, accurate and precise and requires relatively inexpensive instrumentation. The estimation of etravirine in bulk drug and tablet dosage form can be done by this new method. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="UV-spectrophotometric method">UV-spectrophotometric method</a> |
| -- | <a href="green method">green method</a> |
| -- | <a href="eco-friendly solvent ">eco-friendly solvent </a> |
| -- | <a href="etravirine">etravirine</a> |
| -- | <a href="AGREE software">AGREE software</a> |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125265 |
| Host Itemnumber | 112316 |
| Place, publisher, and date of publication | Mumbai Indian Drugs Manufacturer's Association |
| Title | Indian Drugs |
| International Standard Serial Number | 0019-462X |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 23/06/2025 | JP599.6 | 23/06/2025 | 23/06/2025 | Journal Article |