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IN VITRO EVALUATION OF THE CYTOTOXICITY AND BIOCOMPATIBILITY OF VIDANGADI KSHARA ON LYMPHOMA CANCER CELLS (Record no. 132138)
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| 000 -LEADER | |
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| fixed length control field | 01614nam a2200145 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250718b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Pallavi Athavale |
| 245 ## - TITLE STATEMENT | |
| Title | IN VITRO EVALUATION OF THE CYTOTOXICITY AND BIOCOMPATIBILITY OF VIDANGADI KSHARA ON LYMPHOMA CANCER CELLS |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | pp67-75 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | The global leading cause of mortality is cancer, with approximately 10 million cancer-related deaths documented in 2020. Vidangadi kshara (VK), a formulation containing Vidanga, Chitraka, Shunthi, Ghrita, Saindhava and Vacha, is traditionally prescribed for Gulma (lump) and Pleeha vyadhi (spleenomegaly). This research aims to evaluate the potential cytotoxic effects and biocompatibility of Vidangadi kshara against lymphoma cells, while assessing its impact on normal cells.The Vidangadi kshara preparation followed classical methodologies and underwent quality analysis according to standard guidelines before being tested for anticancer properties using the tetrazolium-based MTT assay. In mouse fibroblast L929 cells, VK demonstrated cell viability results comparable to cisplatin. When administered at a dose of 1mg, VK exhibited cytotoxic activity against Daudi and Raji Burkitt lymphoma cells. The percentage of cell viability observed with VK treatment was similar to that achieved with cisplatin treatment. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Vidangadi kshara">Vidangadi kshara</a> |
| -- | <a href="Lymphoma cells ">Lymphoma cells </a> |
| -- | <a href="biocompatibility ">biocompatibility </a> |
| -- | <a href="cytotoxic action ">cytotoxic action </a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Veena B. Kupatib |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 132135 |
| Host Itemnumber | 113083 |
| Main entry heading | Dhanashri S. Dhavale |
| Title | PHYTOCHEMICAL PROFILING AND GC-MS ANALYSIS OF AQUEOUS METHANOL FRACTION OF SEVYACHANDANADI LEPA |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 18/07/2025 | jp758.6 | 18/07/2025 | 18/07/2025 | Journal Article |