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Evaluation of Conflicts of Financial Interest in Publications on the Consumption of High-Intensity Sweeteners and Body-Weight Changes: A Systematic Review (Record no. 132764)

MARC details
000 -LEADER
fixed length control field 02534nam a2200145 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 250911b |||||||| |||| 00| 0 eng d
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Rebeca Cirilo de Lima
245 ## - TITLE STATEMENT
Title Evaluation of Conflicts of Financial Interest in Publications on the Consumption of High-Intensity Sweeteners and Body-Weight Changes: A Systematic Review
300 ## - PHYSICAL DESCRIPTION
Extent pp 648–662
520 ## - SUMMARY, ETC.
Summary, etc. biblio.abstract Context<br/>Diseases related to excessive sugar consumption have become a public health concern. However, there may be a direct association between the consumption of artificial sweeteners and changes in body weight.<br/><br/>Objective<br/>The aim was to evaluate potential industry financial conflicts of interest in publications on the relationship between high-intensity sweetener consumption and changes in body weight in observational and intervention studies.<br/><br/>Data Sources<br/>The systematic review used the Medline, Embase, Cochrane, Scopus, and the VHL (Virtual Health Library) Regional Portal, including the LILACS databases. The PICOS strategy were used in the search strategy for intervention studies and for observational studies used the exposure factor as the criterion.<br/><br/>Data Extraction<br/>Inclusion criteria were observational and intervention studies in adults, without population or health status restrictions, without restriction on the year of publication, but restricted to full articles in Portuguese, English, and Spanish. Exclusion criteria were humans younger than 18 years, cross-sectional studies, and animal and in vitro studies.<br/><br/>Data Analysis<br/>There were extracted effect estimates, odds ratios, and linear associations, quantifying the effects per unit of intake of high-intensity sweeteners. The risk of bias in the intervention studies was assessed using the Cochrane Collaboration Risk of Bias tool (RoB). The Newcastle Ottawa Scale was used for observational studies (case-control and cohort).<br/><br/>Conclusion<br/>Most clinical trials favor using artificial sweeteners and receive contributions from the food industry. Observational studies, for the most part, show that the use of artificial sweeteners is unfavorable. In these studies, there was no sponsorship from the food industry, only from regulatory bodies. This result suggests that studies that had the support of the food industry had their influence on their outcomes.<br/><br/>
654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS
Subject <a href="body weight">body weight</a>
-- <a href="artificial">artificial</a>
-- <a href="sweetener">sweetener</a>
-- <a href=" low calorie"> low calorie</a>
-- <a href=" conflict of interest"> conflict of interest</a>
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Gabriela Bioni e Silva
773 0# - HOST ITEM ENTRY
Host Biblionumber 25311
Host Itemnumber 113491
Place, publisher, and date of publication 2009
Title Nutrition Reviews
International Standard Serial Number 0029-6643
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Location (home branch) Sublocation or collection (holding branch) Date acquired Koha issues (times borrowed) Piece designation (barcode) Koha date last seen Price effective from Koha item type
    Dewey Decimal Classification     SNDT Juhu SNDT Juhu 11/09/2025   jp871.5 11/09/2025 11/09/2025 Journal Article