SNDT WOMEN'S UNIVERSITY
BMK Knowledge Resource Centre
Vithaldas Vidyavihar, Juhu Tara Road,
Santacruz (West) Mumbai - 400049
Osteogenic Effects of Bioactive Compounds Found in Fruits on Mesenchymal Stem Cells: A Review (Record no. 132767)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02223nam a2200145 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250911b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Lia Igel Sodré |
| 245 ## - TITLE STATEMENT | |
| Title | Osteogenic Effects of Bioactive Compounds Found in Fruits on Mesenchymal Stem Cells: A Review |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | pp675–691 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | Phytochemicals, which are bioactive compounds contained in fruits, vegetables, and teas, have a positive effect on human health by having anti-inflammatory, antioxidant, and anticarcinogenic effects. Several studies have highlighted the ability of bioactive compounds to activate key cellular enzymes associated with important signaling pathways related to cell division and proliferation, as well as their role in inflammatory and immunological responses. Some phytochemicals are associated with increased proliferation, differentiation, and expression of markers related to osteogenesis, bone formation, and mineralization by activating various signaling pathways. The objective of this study was to clarify which bioactive compounds present in fruits have osteogenic effects on mesenchymal stem cells and the possible associated mechanisms. A literature search was conducted in the LILACS, MEDLINE, and PubMed databases for pertinent articles published between 2014 and 2024. This review included 34 articles that report the osteogenic effects of various bioactive compounds found in different fruits. All the articles reported that phytochemicals play a role in enhancing the regenerative properties of mesenchymal cells, such as proliferation, osteogenic differentiation, secretion of angiogenic factors, and extracellular matrix formation. This review highlights the potential of these phytochemicals in the prevention and treatment of bone diseases. However, more studies are recommended to identify and quantify the therapeutic dose of phytochemicals, investigate their mechanisms in humans, and ensure their safety and effectiveness for health, particularly for bone health. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="phytochemicals">phytochemicals</a> |
| -- | <a href=" fruit"> fruit</a> |
| -- | <a href="mesenchymal stem cells">mesenchymal stem cells</a> |
| -- | <a href="mesenchymal stromal cells">mesenchymal stromal cells</a> |
| -- | <a href="osteogenesis">osteogenesis</a> |
| -- | <a href=" bones"> bones</a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maria Eduarda Cordebello Gall |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 25311 |
| Host Itemnumber | 113491 |
| Place, publisher, and date of publication | 2009 |
| Title | Nutrition Reviews |
| International Standard Serial Number | 0029-6643 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
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| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 11/09/2025 | jp871.7 | 11/09/2025 | 11/09/2025 | Journal Article |