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Nutrigenetic and Epigenetic Mechanisms of Maternal Nutrition–Induced Glucolipid Metabolism Changes in the Offspring (Record no. 132770)

MARC details
000 -LEADER
fixed length control field 01995nam a2200145 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Peng Jiao
245 ## - TITLE STATEMENT
Title Nutrigenetic and Epigenetic Mechanisms of Maternal Nutrition–Induced Glucolipid Metabolism Changes in the Offspring
300 ## - PHYSICAL DESCRIPTION
Extent pp728–748
520 ## - SUMMARY, ETC.
Summary, etc. biblio.abstract Abstract<br/>Maternal nutrition during pregnancy regulates the offspring’s metabolic homeostasis, including insulin sensitivity and the metabolism of glucose and lipids. The fetus undergoes a crucial period of plasticity in the uterus; metabolic changes in the fetus during pregnancy caused by maternal nutrition not only influence fetal growth and development but also have a long-term or even life-long impact for the offspring. Epigenetic modifications, such as DNA methylation, histone modification, and non-coding RNAs, play important roles in intergenerational and transgenerational effects. In this context, this narrative review comprehensively summarizes and analyzes the molecular mechanisms underlying how maternal nutrition, including a high-fat diet, polyunsaturated fatty acid diet, methyl donor nutrient supplementation, feed restriction, and protein restriction during pregnancy, impacts the genes involved in glucolipid metabolism in the liver, adipose tissue, hypothalamus, muscle, and oocytes of the offspring in terms of the epigenetic modifications. This will provide a foundation for the further exploration of nutrigenetic and epigenetic mechanisms for integrative mother–child nutrition and promotion of the offspring’s health through the regulation of maternal nutrition during pregnancy. Note: This paper is part of the Nutrition Reviews Special Collection on Precision Nutrition.
654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS
Subject <a href="maternal nutrition">maternal nutrition</a>
-- <a href="offspring glucolipid metabolism">offspring glucolipid metabolism</a>
-- <a href=" nutrigenetics"> nutrigenetics</a>
-- <a href="epigenetics">epigenetics</a>
-- <a href=" DNA methylation"> DNA methylation</a>
-- <a href=" histone modification"> histone modification</a>
-- <a href="non-coding RNAs">non-coding RNAs</a>
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Huizhen Lu, MD
773 0# - HOST ITEM ENTRY
Host Biblionumber 25311
Host Itemnumber 113491
Place, publisher, and date of publication 2009
Title Nutrition Reviews
International Standard Serial Number 0029-6643
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
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    Dewey Decimal Classification     SNDT Juhu SNDT Juhu 11/09/2025   jp871.10 11/09/2025 11/09/2025 Journal Article