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Phytoactives for Obesity Management: Integrating Nanomedicine for Its Effective Delivery (Record no. 132789)

MARC details
000 -LEADER
fixed length control field 01867nam a2200145 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Ashok Kumar Mandal,
245 ## - TITLE STATEMENT
Title Phytoactives for Obesity Management: Integrating Nanomedicine for Its Effective Delivery
300 ## - PHYSICAL DESCRIPTION
Extent Pages 1152–1170
520 ## - SUMMARY, ETC.
Summary, etc. biblio.abstract Obesity is a global health concern that requires urgent investigation and management. While synthetic anti-obesity medications are available, they come with a high risk of side-effects and variability in their efficacy. Therefore, natural compounds are increasingly being used to treat obesity worldwide. The proposition that naturally occurring compounds, mainly polyphenols, can be effective and safer for obesity management through food and nutrient fortification is strongly supported by extensive experimental research. This review focuses on the pathogenesis of obesity while reviewing the efficacy of an array of phytoactives used for obesity treatment. It details mechanisms such as enzyme inhibition, energy expenditure, appetite suppression, adipocyte differentiation, lipid metabolism, and modulation of gut microbiota. Comprehensive in vitro, in vivo, and preclinical studies underscore the promise of phytoactives in combating obesity, which have been thoroughly reviewed. However, challenges, such as poor bioavailability and metabolism, limit their potential. Advances in nanomedicines may overcome these constraints, offering a new avenue for enhancing the efficacy of phytoactives. Nonetheless, rigorous and targeted clinical trials are essential before applying phytoactives as a primary treatment for obesity.
654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS
Subject <a href="phytoactive">phytoactive</a>
-- <a href=" complementary and alternative medicine"> complementary and alternative medicine</a>
-- <a href="obesity">obesity</a>
-- <a href="metabolism">metabolism</a>
-- <a href=" gut microbiota"> gut microbiota</a>
-- <a href="nanomedicines">nanomedicines</a>
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Ankit Sahoo
773 0# - HOST ITEM ENTRY
Host Biblionumber 25311
Host Itemnumber 113494
Place, publisher, and date of publication 2009
Title Nutrition Reviews
International Standard Serial Number 0029-6643
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Location (home branch) Sublocation or collection (holding branch) Date acquired Koha issues (times borrowed) Piece designation (barcode) Koha date last seen Price effective from Koha item type
    Dewey Decimal Classification     SNDT Juhu SNDT Juhu 11/09/2025   JP873.12 11/09/2025 11/09/2025 Journal Article