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Preclinical Models of Lung Fibrosis: A Gateway for Clinical Research (Record no. 133017)
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| fixed length control field | 01714nam a2200145 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
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| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Lucy Mohapatra |
| 245 ## - TITLE STATEMENT | |
| Title | Preclinical Models of Lung Fibrosis: A Gateway for Clinical Research |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | pp1-11 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | Lung fibrosis (LF) is a form of a severe respiratory disorder that has a survival period of about three to five years after<br/>diagnosis. Lung fibrosis is a group of lung disorders characterized by progressive scarring of alveolar tissues. Many<br/>models, such as irradiation, exposure to toxins like bleomycin, silica, and fluorescein isothiocyanate and the<br/>expression of particular genes using viral vectors or transgenic systems are utilized to examine this disease. A recent<br/>model involving repetitive bleomycin lung injury has also been developed, leading to significant lung fibrosis,<br/>specifically hyperplasia of alveolar epithelial cells, and persistent abnormal remodelling even after the removal of the<br/>stimulus. This model contributes significantly to the pre-existing animal models for lung fibrosis, allowing for the<br/>study of temporal heterogeneity and long-term effects. Various in vitro models such as in vitro 2D tissue culture plastic<br/>model along with in vitro 3D hydrogel system model and recently developed humanized model has also been<br/>discussed in this review. Each of these reviewed models provides a valuable tool for investigating different aspects of<br/>lung fibrosis. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Fibrotic Lung">Fibrotic Lung</a> |
| -- | <a href="Bleomycin">Bleomycin</a> |
| -- | <a href="Silica">Silica</a> |
| -- | <a href=" Fibroblasts"> Fibroblasts</a> |
| -- | <a href="Isothiocyanate and In vitro model">Isothiocyanate and In vitro model</a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Deepak Mishra |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125267 |
| Host Itemnumber | 114071 |
| Place, publisher, and date of publication | Rajasthan Health Education Bureau |
| Title | Journal of Hospital Pharmacy |
| International Standard Serial Number | 2348-7704 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 13/10/2025 | jp946.1 | 13/10/2025 | 13/10/2025 | Journal Article |