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SUBCHRONIC ORAL TOXICITY STUDY IN WISTAR RATS OF SHILAJITWADI VATI, A HERBOMETALLIC FORMULATION (Record no. 133046)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01613nam a2200145 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 251016b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mahalaxmi M. |
| 245 ## - TITLE STATEMENT | |
| Title | SUBCHRONIC ORAL TOXICITY STUDY IN WISTAR RATS OF SHILAJITWADI VATI, A HERBOMETALLIC FORMULATION |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | Page No. 52-57 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | hilajitwadi vati, a traditional herbometallic formulation, is used for treating various ailments. This subchronic toxicity study evaluated its safety during extended oral administration due to the inclusion of heavy metals. In compliance with OECD guideline 408, animals were divided into four groups: three received Shilajitwadi vati at doses of 51.36, 205.44, and 513.6 mg kg-1 for 90 days, while the control group received only the vehicle. All the animals showed no signs of toxicity or mortality throughout the study, with steady weight gain and increased feed and water intake. Urine samples, haematological and biochemical parameters were analyzed on day 91, revealing no significant differences between treated and control groups. All data were analysed by one way ANOVA using GraphPad Prism. Histopathological examination showed no adverse effects on vital organs and no metal accumulation in tissues supporting the safety of Shilajitwadi vati. These findings suggest that Shilajitwadi vati is a safe therapeutic option for prolonged use. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Ayurveda ">Ayurveda </a> |
| -- | <a href="Herbometallic ">Herbometallic </a> |
| -- | <a href="shilajitwadi vati ">shilajitwadi vati </a> |
| -- | <a href="subchronic oral toxicity">subchronic oral toxicity</a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shubhangi H. Pawa |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125265 |
| Host Itemnumber | 114019 |
| Place, publisher, and date of publication | Mumbai Indian Drugs Manufacturer's Association |
| Title | Indian Drugs |
| International Standard Serial Number | 0019-462X |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 16/10/2025 | jp940.5 | 16/10/2025 | 16/10/2025 | Journal Article |