SNDT WOMEN'S UNIVERSITY
BMK Knowledge Resource Centre
Vithaldas Vidyavihar, Juhu Tara Road,
Santacruz (West) Mumbai - 400049
Effectiveness of disease-modifying agents in ameliorating multiple sclerosis – A cross-sectional observational study (Record no. 133108)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02219nam a2200157 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 251029b |||||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Jayachandran |
| 245 ## - TITLE STATEMENT | |
| Title | Effectiveness of disease-modifying agents in ameliorating multiple sclerosis – A cross-sectional observational study |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | pp90-96 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. biblio.abstract | BACKGROUND: <br/>Multiple sclerosis (MS) – A chronic inflammatory demyelinating disorder of the central nervous system is notorious for causing progressive neurological deterioration. This affects the quality of life of these patients and their productivity. Various oral and injectable disease-modifying drugs (DMDs) are available for the treatment of MS. In spite of availability of many drugs, the quality of life of these patients continues to be perturbing. The present study was undertaken to assess the effectiveness of common therapy in MS.<br/><br/>METHODS: <br/>A single-center cross-sectional study was conducted from 2020 to 2021. Seventy-one MS patients on DMDs were recruited. Relevant clinical details were collected from the electronic medical records, and a quality-of-life questionnaire was administered telephonically. Assessment of drugs being prescribed, treatment effectiveness, and adverse drug reactions were calculated as frequency and percentage.<br/><br/>RESULTS: <br/>Female cases were 64.8%. 77.5% were relapsing-remitting type of MS. The initial presenting complaints varied from visual disturbances in 28.16%, paresthesia in 25.35%, and ataxia in 21.12%. No relapse episodes were reported in 21.12% of cases. 33.8% faced physical disabilities and 9.9% cognitive disabilities. 2.81% cases opined that their quality of life is good.<br/><br/>CONCLUSIONS: <br/>Drug therapy is beneficial in providing remission and reducing relapse rates in MS. DMDs are effective in reducing the debilitating symptoms and preventing the progression of the disease, when begun immediately after the diagnosis is made. |
| 654 ## - SUBJECT ADDED ENTRY--FACETED TOPICAL TERMS | |
| Subject | <a href="Disabilities ">Disabilities </a> |
| -- | <a href="disease-modifying drugs">disease-modifying drugs</a> |
| -- | <a href="multi sclerosis">multi sclerosis</a> |
| -- | <a href="multiple sclerosis quality of life-54 ">multiple sclerosis quality of life-54 </a> |
| -- | <a href="quality of life">quality of life</a> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mamatha |
| 773 0# - HOST ITEM ENTRY | |
| Host Biblionumber | 125270 |
| Host Itemnumber | 114201 |
| Place, publisher, and date of publication | Mumbai Wolters Kluwer India |
| Title | Indian Journal of Pharmacology |
| International Standard Serial Number | 0253-7613 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Location (home branch) | Sublocation or collection (holding branch) | Date acquired | Koha issues (times borrowed) | Piece designation (barcode) | Koha date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | SNDT Juhu | SNDT Juhu | 29/10/2025 | JP984.4 | 29/10/2025 | 29/10/2025 | Journal Article |