Raksha K. Rao <br/><br/>
TECHNIQUES AND ALGORITHMS FOR STRUCTURE-BASED VIRTUAL SCREENING (SBVS): AN OVERVIEW 

 - P 7-17 
<br/><br/> Today, the world of science is constantly challenged with new genomics, which in turn is responsible for new disease-causing targets. Hence, there is a need for developing drugs acting against such targets. Computational methods are proving to be a mainstay in the drug discovery process, mainly through virtual screening. This review discusses about the recent advancements in structure-based drug design with reference to Virtual Screening along with its procedures from ligand preparation and protein preparation, docking, scoring function, databases, and virtual (VS) algorithms. Application of Structure-based VS in combination with other virtual screening techniques has also been highlighted in this review. 
<br/><br/><label>Subjects--Facted Index Terms: </label><br/> Virtual Screening <br/>structure-based virtual screening <br/>docking <br/>library preparation<br/>scoring functions<br/>algorithms <br/>combined application