TY  - BOOK
AU  - Raksha K. Rao
AU  - Somdatta Y. Chaudhari
TI  - TECHNIQUES AND ALGORITHMS FOR STRUCTURE-BASED VIRTUAL SCREENING (SBVS): AN OVERVIEW
KW  -  Virtual Screening
KW  - structure-based virtual screening
KW  - docking
KW  - library preparation
KW  - scoring functions
KW  - algorithms
KW  - combined application
N2  - Today, the world of science is constantly challenged with new genomics, which in turn is responsible for new disease-causing targets. Hence, there is a need for developing drugs acting against such targets. Computational methods are proving to be a mainstay in the drug discovery process, mainly through virtual screening. This review discusses about the recent advancements in structure-based drug design with reference to Virtual Screening along with its procedures from ligand preparation and protein preparation, docking, scoring function, databases, and virtual (VS) algorithms. Application of Structure-based VS in combination with other virtual screening techniques has also been highlighted in this review
ER  -