Bhumika Arora <br/><br/>
Evaluation of the antimicrobial potential of Catharanthus roseusextract 

 - P.334-338 
<br/><br/> Catharanthus    roseusL.    (Apocyanaceae),    also    known    as Madagascar  periwinkle,  is  an  evergreen  herb  with  therapeutic qualities.  The  present  study  investigated  the  antibacterial  activity of C.  roseus leaf ethanol  extract  (Cr-LEE)  against E.  coli.The result  indicated  significant  growth  inhibitory  activity  of Cr-LEE on E.  coli.  The  effects  were  dose-dependent.  From  our  earlier research,  GC/MS (Gas Chromatography-Mass Spectrometry)  was also  used  to  determine the  significant  phytoconstituents  in  the extract.  The  secondary  metabolites  present  in  the  extract  may individually  or  synergistically  be  responsible  for  the  antibacterial action of C. roseus. 
<br/><br/><label>Subjects--Facted Index Terms: </label><br/>Catharanthus   roseus<br/>Escherichia   coli<br/>Growth inhibition<br/>Leaf extract