TY  - BOOK
AU  - Laura Vresk
TI  - Micronutrient status in children aged 6–59 months with severe wasting and/or nutritional edema: implications for nutritional rehabilitation formulations
KW  - Severe malnutrition
KW  - severe acute malnutrition
KW  - severe wasting
KW  - nutritional edema
KW  - kwashiorkor
KW  - marasmus
KW  - pediatric
KW  - therapeutic feeds
KW  - micronutrient status
KW  - micronutrient deficiency
KW  - micronutrient toxicity
KW  - sodium
KW  - potassium,
KW  - calcium
KW  - phosphorus
KW  - magnesium
KW  - iron
KW  - copper
KW  - zinc
KW  - selenium
KW  - iodine
KW  - thiamine
KW  - riboflavin
KW  -  niacin
KW  - pantothenic acid
KW  - vitamin B6
KW  - folic acid
KW  - vitamin B12
KW  - biotin
N2  - Undernutrition remains a global struggle and is associated with almost 45% of deaths in children younger than 5 years. Despite advances in management of severe wasting (though less so for nutritional edema), full and sustained recovery remains elusive. Children with severe wasting and/or nutritional edema (also commonly referred to as severe acute malnutrition and part of the umbrella term “severe malnutrition”) continue to have a high mortality rate. This suggests a likely multifactorial etiology that may include micronutrient deficiency. Micronutrients are currently provided in therapeutic foods at levels based on expert opinion, with few supportive studies of high quality having been conducted. This narrative review looks at the knowledge base on micronutrient deficiencies in children aged 6–59 months who have severe wasting and/or nutritional edema, in addition to highlighting areas where further research is warranted (See “Future Directions” section)
ER  -