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Sebum Secretion: The Missing Chain in the Pathogenesis of Obesity

By: Description: Pages 1540–1542Subject(s): In: Nutrition Reviews 2009Summary: Every day, a significant amount of fat is excreted through the skin in the form of sebum. However, this significant calorie loss, which may amount to up to 500 kcal/day in individuals with greasy skin, has often been disregarded in obesity studies. The most important theoretical models of the pathogenesis of obesity, the Energy Balance Model and the Carbohydrate-Insulin Model, need to be re-evaluated taking this into account, and “energy loss through the skin” should be included in the energy-balance equation. This overlooked pathway might partially explain discrepancies in energy balance measurements. Factors affecting sebum production may also affect weight; however, this requires further research.
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Item type Current library Call number Vol info Status Barcode
Journal Article SNDT Juhu Available jp932.11
Periodicals SNDT Juhu P 641.1/ NR (Browse shelf(Opens below)) Vol. 83, No. 8 (01/08/2025) Available JP932

Every day, a significant amount of fat is excreted through the skin in the form of sebum. However, this significant calorie loss, which may amount to up to 500 kcal/day in individuals with greasy skin, has often been disregarded in obesity studies. The most important theoretical models of the pathogenesis of obesity, the Energy Balance Model and the Carbohydrate-Insulin Model, need to be re-evaluated taking this into account, and “energy loss through the skin” should be included in the energy-balance equation. This overlooked pathway might partially explain discrepancies in energy balance measurements. Factors affecting sebum production may also affect weight; however, this requires further research.

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