| 000 | 02218nam a2200181 4500 | ||
|---|---|---|---|
| 003 | OSt | ||
| 005 | 20241022111631.0 | ||
| 008 | 241022b |||||||| |||| 00| 0 eng d | ||
| 100 | _aMukesh Yadav | ||
| 245 | _aSynbiotics as potent functional food: recent updates on therapeutic potential and mechanistic insight | ||
| 300 | _ap1–15 | ||
| 520 | _aSynbiotics are the specific mixtures of prebiotics with probiotics intended to give health benefits to the host by stabilizing and supporting the gut microbiota.The prebiotic substance used in the synbiotics selectively favors the growth and metabolite production of probiotics. Gut microbiome dysbiosis may lead to generation and progression of various chronic diseases. Synbiotics act synergistically to modulate the gut ecosystem for improvement of metabolic health of the host. Probiotics have been found promising against various diseases being safer, effective, as an alternative or combinatorial therapy. Specific combinations of probiotics with suitable prebiotic substrate as synbiotics, may be the more effective therapeutic agents that can provide all benefits of probiotics as well as prebiotics. Though, effective combinations, dosage, mechanism of action, safety, cost effectiveness and other clinical investigations are required to be established along with other relevant aspects. Synbiotics have the potential to be functional food of importance in future. Present review summarizes the mechanistic overview of synbiotics related to gut microbiota, therapeutic potential and promising health benefits for human illnesses according to the available literature. In present scenario, synbiotics are more promising future alternatives as therapeutics to maintain healthy microbiota inside the host gut which directly affects the onset or development ofrelated disorders or diseases. | ||
| 654 |
_aSynbiotics _aFunctional _afood Gut microbiome _aIntestinal health _aMechanism _aTherapeutic potential |
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| 700 |
_a Nirmala Sehrawat _a Anil Kumar Sharma _a Sunil Kumar _a Rajbir Singh _a Ashwani Kumar _aAmit Kumar |
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| 773 | 0 |
_080310 _9110104 _dGermany Springer _oJP337 _tJournal of Food Science and Technology _x0022-1155 |
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| 942 | _cJA | ||
| 942 | _2ddc | ||
| 999 |
_c129851 _d129851 |
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