000 02066nam a2200169 4500
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100 _aSmriti Singh
245 _aEfficacy of Swarna-prash in combating perinatal oxidative stress and its compatibility in newborns
300 _ap958-969
520 _aAll neonates are exposed to a variable degree of oxidative stress that may result in cellular, tissue, or organ damage due to a low-efficient antioxidant system. The present study aimed to evaluate the effect of licked Swarna-prash, comprising 15 mg Swarna-bhasma (incinerated gold particles) mixed with 1 mL honey and 0.5 mL Ghrita (butter oil), given in perinatal oxidative stress. A randomized case-control study ensued after the microanalysis of InAuPs (Incinerated Aurum Particles) and Swarna-prash. Ninety newborns were registered, considering the inclusion and exclusion criteria, and divided into three groups. The single dose of Swarna-prash was given once a day in Group A and thrice a day in Group B. Due to ethical issues, nothing was given except mother milk in Group - C (control group). Venous blood samples were collected from the umbilical cord after birth and 48 h for complete blood counts (CBC), Liver function test (LFT), Renal function tests (RFT), and antioxidant enzymes. The Swarna-bhasma consisted of crystallite-size InAuPs ranging from 30.86 to 114.02 nm. The intergroup analysis of CBC, LFT, RFT, SOD, GSH, and catalase values shows in significant (p>0.05) variation except for the serum bilirubin and SOD in group-B v/s C, offers significant mean values (p<0.05). Finally, it can be inferred that Swarna-prash opposes neonatal perinatal oxidative stress, seems nontoxic, reduces the incidence of physiological jaundice, and is bio-compatible.
654 _a Microanalysis,
_aNewborns,
_a Oxidative-stress,
_aSwarna-bhasma,
_a Swarna-prash
773 0 _0125286
_9110691
_dNew Delhi NISCAIR
_oJP399
_tIndian Journal of Traditional Knowledge
_x0972-5938
942 _cJA
942 _2ddc
999 _c130578
_d130578