000			01411nam a2200181 4500
003			OSt
005			20250114113237.0
008			250114b |||||||| |||| 00| 0 eng d
100			_aArchana
245			_aSYNTHESIS AND IN VIVO EVALUATION OF SOME NEW PYRAZOL INDOLES, THEIR AZO AND MANNICH SALTS AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS
300			_aP. 21-28
520			_aThis paper deals with the design, synthesis and biological evaluation of new pyrazolyl indole derivatives including azo compounds and Mannich salts. The work of this research could lead to potentially useful analgesic and anti-inflammatory agents. Utilizing the synthetic route illustrated in Fig. 1, compounds 1 to 30 have been synthesized. All synthesized compounds have been characterized using TLC, elemental analysis for C, H and N and spectral methods involving IR, 1H-NMR, and mass spectroscopy. All tests conducted on standard models in vivo have exhibited excellent analgesic and anti-inflammatory activity, thus suggesting potential therapeutic applications.
654			_aPyrazolyl indoles _aazo compounds _aMannich salts _aspectral studies _aanalgesic agents _aanti-inflammatory agents _aacute toxicity
700			_a Meenakshi Yadav _aSakshi Chaudhary
773	0		_0125265 _9111177 _dMumbai Indian Drugs Manufacturer's Association _oJP490 _tIndian Drugs _x0019-462X
942			_cJA
942			_2ddc
999			_c130734 _d130734