| 000 | 01004nam a2200121 4500 | ||
|---|---|---|---|
| 008 | 250228b |||||||| |||| 00| 0 eng d | ||
| 100 | _aYanping Li | ||
| 245 | _aShikimate Kinase 1 from Klebsiella pneumoniae as a New Drug Target Enzyme: Insights from Comparative Modeling and Molecular Dynamics | ||
| 520 | _aKlebsiella pneumoniae, a Gram-negative bacterium, is an established nosocomial pathogen that is particularly dangerous to immunosuppressed individuals, causing diseases such as sepsis, pneumonia, urinary tract infections and respiratory tract infections. The emergence of multidrug resistant strains of this bacterium poses a significant challenge to current therapeutic strategies, highlighting the urgent need for new drug targets. | ||
| 654 |
_aArray, _aShikimate Kinase 1 _aAlphaFold2 _a, Molecular dynamics simulations |
||
| 773 | 0 |
_0125266 _9111205 _dBanglore Association of Pharmaceutical Tearchers of India _tIndian Journal of Pharmaceutical Education and Research _x0019-5464 |
|
| 942 | _cJA | ||
| 999 |
_c131239 _d131239 |
||