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100			_aRenato Constantino dos Santos Souza
245			_aPhytochemical profiles and cytotoxicity evaluation of the ethanolic extract of Malpighia emarginataleaves: Potential for its therapeutic use
300			_aP.294-301
520			_aThe search for new natural compounds with relevant therapeutic properties has increased in recent years. The objective of this study was to investigate the biological properties of the ethanolic extract of Malpighia emarginataleaves. For this, phytochemical assays, high-performance thin layer chromatography (HPTLC), high-performance liquid chromatography (HPLC), antioxidant activity analysis using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and cytotoxicity by hemolysis, and chorioallantoic membrane (CAM) studies were performed. Through qualitative analyses, phenolic compounds and alkaloids were identified, and by quantitative analyses, 92.52, 2.02, and 0.59 μg/mL were found for total flavonoids, total alkaloids, and total phenols, respectively. HPTLC showed the presence of the flavonoids catechin and gallic acid, while HPLC identified myricetin and quercetin. The extract showed a high antioxidant capacity of 80.77% by DPPH. Moreover, low cytotoxicity of the extract at 10% was observed by hemolysis and CAM assay. Our results indicate that the ethanolic extract of M. emarginataleaves is a potential candidate for therapeutic use due to the presence of important bioactive compounds, high antioxidant activity and low cytotoxicity.
654			_aAcerola _a Alcoholic extract, _aDPPH _aHPLC _aHPTLC, _ahytochemical compounds
700			_aRodrigo Augusto Cristóvão Ferreira
773	0		_0125285 _9109968 _dNew Delhi NISCAIR _tIndian Journal of Natural Products and Resources _x0976-0504
942			_cJA
999			_c131259 _d131259