000			01639nam a2200145 4500
008			250320b |||||||| |||| 00| 0 eng d
100			_aR K Dedar
245			_aManagement of seasonal dermatitis in horses by using leaf extract of Aerva javanica
300			_ap.154-161
520			_aOccurrence of seasonal allergic dermatitis, especially insect bite hypersensitivity and atopic dermatitis are very common in horses. At present there is no satisfactory treatment is available for management of these skin allergies. Plant flavonoids such as quercetin, kaempferol and their glycoside derivatives have been reported for their anti allergic and anti-inflammatory properties. In present study we have prepared an extract from the leaves of Aerva javanica, which was found effective to manage clinical cases of seasonal allergic dermatitis in horses. Clinical signs of the allergic dermatitis in horses were alopecia, thickening of skin and itching. On histopathological examination of skin biopsy samples taken from the clinical cases epidermal hyperplasia, orthokeratotic and parakeratotic hyperkeratosis, spongiosis, occasional trichomalacia, multifocal areas of aggregation of lymphocytes with or without infiltration of eosinophils were observed. Mass spectrometer analysis of more purified extract suggested a glycoside of kaempferol may be an active ingredient of the extract
654			_aAerva javanica _aAlopecia _aDermatitis _aFlavonoid _aHorse
700			_aNaveen Kumar
773	0		_0125286 _9109623 _dNew Delhi NISCAIR _tIndian Journal of Traditional Knowledge _x0972-5938
942			_cJA
999			_c131441 _d131441