000 01674nam a2200133 4500
008 250513b |||||||| |||| 00| 0 eng d
100 _aDhanashree P. Sanapa*
245 _aNAVIGATING NANO LANDSCAPE: A COMPREHENSIVE REVIEW OF CUBOSOMES IN DRUG DELIVERY AND BEYOND
300 _ap8-19
520 _aCubosomes are nanostructured liquid crystalline particles formed from specific combinations of amphiphilic lipids, and they are used as biocompatible drug delivery vehicles. Cubosomes typically have a diameter of about 200 nm, making them suitable for various biomedical applications. They are composed of amphiphilic lipids, which have both hydrophilic and hydrophobic parts, stabilizers to maintain their structure, and water. The specific ratios of these components are crucial for forming and stabilizing the cubosomal structure. Cubosomal preparations often exhibit a viscous yet transparent appearance, which can be advantageous for their ease of handling and potential applications. The unique three-dimensional honeycomb structure of cubosomes provides them with a large surface area. This is beneficial for loading a significant amount of bioactive substances, enhancing their therapeutic potential. Cubosomes can be prepared using relatively straightforward methods, which is advantageous for scalability and industrial production. This review article provides an overview of cubosomes, their types, composition as well as pharmaceutical applicability.
654 _aCubosomes
_aDrug delivery
_aApplication
_aNanoformulation
773 0 _0125265
_9112354
_dMumbai Indian Drugs Manufacturer's Association
_tIndian Drugs
_x0019-462X
942 _cJA
999 _c131678
_d131678