000			01605nam a2200145 4500
008			250805b |||||||| |||| 00| 0 eng d
100			_aNguyen Thi Thu Thuy
245			_aOptimization of the extraction process of antioxidant compositions from Glycyrrhiza uralensis using the response surface method Authors
300			_app307-314
520			_aThis study aimed to optimise and evaluate the antioxidant activity of Glycyrrhiza uralensis root extract using a simple heating method. The optimisation of extraction conditions was conducted using the Response Surface Methodology (RSM) and a Box-Behnken design (BBD), focusing on variables such as temperature, ethanol concentration, extraction time, and solvent-to-material ratio. The total phenolic content (TPC) and total flavonoid content (TFC) were used as response variables. The optimal extraction conditions were determined to be a temperature of 58°C, ethanol concentration of 56%, a liquid-to-solid ratio of 30 mL/g, and an extraction time of 190 minutes, resulting in TPC and TFC values of 158.81 mg GAE/g and 122.15 mg QE/g, respectively. The extract exhibited considerable DPPH and hydroxyl radical scavenging effects. These findings suggest that the optimized extraction method not only simplifies the process but also enhances the scalability and cost-effectiveness of industrial applications.
654			_a Antioxidant _aBox-Behnken _aGlycyrrhiza uralensis, _a Response surface method
700			_aQuach Thi Quynh
773	0		_0125285 _9113116 _dNew Delhi NISCAIR _tIndian Journal of Natural Products and Resources _x0976-0504
942			_cJA
999			_c132365 _d132365