000			02381nam a2200145 4500
008			250910b |||||||| |||| 00| 0 eng d
100			_a Faranak TaghipourSheshdeh
245			_aThe Effect of Chia Seed on Blood Pressure, Body Composition, and Glycemic Control: A GRADE-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials
300			_aPP448-465
520			_aContext Numerous studies have demonstrated the positive effects on metabolic factors of consuming chia seeds. However, the results of clinical trials have been inconsistent. Objective The aim of this study was to conduct a systematic review and meta-analysis of available randomized controlled trials to explore the effects of chia seed consumption on body weight (BW), body composition, blood pressure, and glycemic control. Data Sources A comprehensive search was conducted on the Scopus, PubMed, Medline via Ovid, ISI Web of Science, and Scholar Google databases up to August 2023. Data Extraction The outcomes of interest included systolic blood pressure (SBP), diastolic blood pressure (DBP), BW, body mass index (BMI), body fat percentage, waist circumference (WC), fasting blood glucose (FBG), and hemoglobin A1c (HbA1c). Data Analysis Weighted mean difference (WMD) and 95% CIs were used to determine the effect size. Results A total of 8 eligible studies were included in the analysis. The findings revealed a significant reduction in SBP (WMD: −7.19 mmHg; 95% CI, −10.63 to −3.73; P < .001) and DBP (WMD: −6.04 mmHg, 95% CI, −9.58 to −2.49; P = .001). However, no significant effects were observed on BW, body fat percentage, WC, BMI, FBG, and HbA1c. Subgroup analysis indicated that the effect of chia seed on SBP was significant in participants with a baseline SBP of less than 140 mmHg, but the effect was not dependent on the administered dose. Conclusion Chia seed consumption has positive effects on SBP and DBP but does not significantly impact BW, body composition, or glycemic parameters. However, the limited amount of data from included studies should be considered as a limitation while interpreting these findings.
654			_achia seed _asystolic blood pressure _a body weight _a blood glucose
700			_a Mehrdad Behzadi
773	0		_025311 _9113490 _d2009 _tNutrition Reviews _x0029-6643
942			_cJA
999			_c132748 _d132748