000			01966nam a2200145 4500
008			250911b |||||||| |||| 00| 0 eng d
100			_aManel Fa-Binefa
245			_aMediterranean Diet and Risk of Hip Fracture: A Systematic Review and Dose-Response Meta-Analysis
300			_a Pages 1133–1143
520			_aContext Hip fractures are a major public health concern. Understanding their epidemiologic and biological links with diet and cardiovascular risk may have important implications for prevention. Objective To assess the dose-response association of Mediterranean diet (MD) adherence with the risk of hip fracture. Data Sources A systematic search was conducted in the PubMed, Scopus, and Web of Science databases for prospective studies. Search terms were “Mediterranean Diet” and “Fracture.” Data extraction Data were extracted from 8 studies, encompassing 15 cohorts that included 503 174 individuals. Methodological quality was assessed using the Risk of Bias in Nonrandomized Studies of Interventions. Data Analysis The “meta” and “dosresmeta” packages were used in R Studio Software. The results demonstrated that high and moderate MD adherence were associated with a reduced risk of hip fracture (relative risk [RR] = 0.71 [95% CI, 0.55-0.91]; and RR = 0.78[(95% CI, 0.65-0.93], respectively). The effect of the association was similar in men and women. The dose-response pattern of the association was linear: each point increase in MD adherence was associated with a 5.25% reduction in hip fracture risk. Conclusions Adherence to MD is associated with a reduction in hip fracture risk, following a linear dose-response pattern. This supports the promotion of this dietary pattern for improving bone health.
654			_aMediterranean diet _a hip fracture _a meta-analysis _a systematic review
700			_aAlbert Clara
773	0		_025311 _9113494 _d2009 _tNutrition Reviews _x0029-6643
942			_cJA
999			_c132787 _d132787