000			01341nam a2200133 4500
008			250912b |||||||| |||| 00| 0 eng d
100			_aDilem Tuğal Aslan
245			_aThe Therapeutic Potential of Theobromine in Obesity: A Comprehensive Review
300			_ap859–868
520			_aObesity, characterized by chronic low-grade inflammation, is a significant health concern. Phytochemicals found in plants are being explored for therapeutic use, particularly in combating obesity. Among these, theobromine, commonly found in cocoa and chocolate, shows promise. Although not as extensively studied as caffeine, theobromine exhibits positive effects on human health. It improves lipid profiles, aids in asthma treatment, lowers blood pressure, regulates gut microbiota, reduces tumor formation, moderates blood glucose levels, and acts as a neuroprotective agent. Studies demonstrate its anti-obesity effects through mechanisms such as browning of white adipose tissue, activation of brown adipose tissue, anti-inflammatory properties, and reduction of oxidative stress. This study aims to suggest theobromine as a potential therapeutic agent against obesity-related complications.
654			_atheobromine _aobesity _abrowning _aanti-inflammatory _aantioxidant
773	0		_025311 _9113493 _d2009 _tNutrition Reviews _x0029-6643
942			_cJA
999			_c132797 _d132797