000 01532nam a2200133 4500
008 250912b |||||||| |||| 00| 0 eng d
100 _aDilek Sivri
245 _aEffect of Fatty Acids on Glucose Metabolism and Type 2 Diabetes
300 _ap897–907
520 _aType 2 diabetes is an inflammatory, non-infectious disease characterized by dysfunctional pancreatic β-cells and insulin resistance. Although lifestyle, genetic, and environmental factors are associated with a high risk of type 2 diabetes, nutrition remains one of the most significant factors. Specific types and increased amounts of dietary fatty acids are associated with type 2 diabetes and its complications. Dietary recommendations for the prevention of type 2 diabetes advocate for a diet that is characterized by reduced saturated fatty acids and trans fatty acids alongside an increased consumption of monounsaturated fatty acids, polyunsaturated fatty acids, and omega-3 fatty acids. Although following the recommendations for dietary fatty acid intake is important for reducing type 2 diabetes and its related complications, the underlying mechanisms remain unclear. This review will provide an update on the mechanisms of action of fatty acids on glucose metabolism and type 2 diabetes, as well as dietary recommendations for the prevention of type 2 diabetes.
654 _afatty acids
_aglucose metabolism
_aınsulin resistance
_atype 2 diabetes
_adietary recommendations
773 0 _025311
_9113493
_d2009
_tNutrition Reviews
_x0029-6643
942 _cJA
999 _c132810
_d132810