000			01554nam a2200145 4500
008			251003b |||||||| |||| 00| 0 eng d
100			_aManisha Singh
245			_aDEVELOPMENT AND ASSESSMENT OF ADENIUM OBESUM FLOWER EXTRACT-BASED OINTMENT FOR ANTIFUNGAL ACTIVITY
300			_aPage No. 56-63
520			_aThis study has been carried out on the formulation development and evaluation of ointment of flower extract of Adenium obesum for its anti-fungal activity. The extraction was done using ethyl alcohol. Six different ointment formulations were prepared and assessed for physical appearance, drug contents, viscosity, pH, spreadability, stability, drug release and in vitro drug diffusion. All formulations showed excellent stability as their drug contents (96.26 - 97.31 %), viscosity (524.25 - 529.23 cP), pH (6.2 - 6.6), spreadability (12 - 14) and in vitro drug diffusion (82.34 - 84.84 %) were found within the range. In long term stability study, it was found that the formulations F3, F4, F5 & F6 were most prominent formulations. The antifungal activity of formulations was found to be in a dose dependent manner. Therefore, we concluded that the formulation might be utilized in the management of fungal infections i.e., dermatitis, pruritis, etc.
654			_aCyclodextrin _aliquid paraffin _aemulsion physical stabillity _aglobule size analysis _ainclusion complexation
700			_aNeha Singhb
773	0		_0125265 _9114075 _dMumbai Indian Drugs Manufacturer's Association _tIndian Drugs _x0019-462X
942			_cJA
999			_c132974 _d132974