000 01186nam a2200145 4500
005 20251017055818.0
008 251017b |||||||| |||| 00| 0 eng d
100 _aJalal Hejazi
245 _aSebum Secretion: The Missing Chain in the Pathogenesis of Obesity
300 _aPages 1540–1542
520 _aEvery day, a significant amount of fat is excreted through the skin in the form of sebum. However, this significant calorie loss, which may amount to up to 500 kcal/day in individuals with greasy skin, has often been disregarded in obesity studies. The most important theoretical models of the pathogenesis of obesity, the Energy Balance Model and the Carbohydrate-Insulin Model, need to be re-evaluated taking this into account, and “energy loss through the skin” should be included in the energy-balance equation. This overlooked pathway might partially explain discrepancies in energy balance measurements. Factors affecting sebum production may also affect weight; however, this requires further research.
654 _asebum
_a obesity
_a energy balance model
_acarbohydrate–insulin model
773 0 _025311
_9113882
_d2009
_tNutrition Reviews
_x0029-6643
942 _cJA
999 _c133062
_d133062