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100			_aAbarna Balasubramani
245			_aADVANCED STRUCTURAL AND TOPOGRAPHICAL INSIGHTS INTO DIFFERENT STAGES OF MUTHUCHIPPI PARPAM USING FESEM AND HRTEM ANALYSIS
300			_aPage No. 36-42
520			_aPearl Oyster Shells (Muthuchippi) are widely used in Siddha medicine for their therapeutic properties, primarily due to their high calcium content and bioactive compounds. This study aimed to analyze the topographic morphology and elemental composition of Muthuchippi Parpam (ash) at different processing stages. Field emission scanning electron microscopy revealed a progressive reduction in particle size, resulting in nano-sized particles with irregular, sheet-like structures. High-resolution transmission electron microscopy showed the nano-range size (94.15 ± 10.54 nm) and crystalline structure, while selected area electron diffraction indicated well-defined bright spots and diffraction rings. Energy dispersive spectroscopy identified calcium as the dominant element (70.66–75.54 wt. %) with notable copper presence (24–28.81 wt. %), minor zinc and selenium impurities, and no detectable magnesium. These findings highlight the successful transformation of oyster shells into a bioactive nanostructured material (Muthuchippi Parpam), enhancing its potential for Siddha medicinal applications.
654			_aFESEM analysis _aHRTEM analysis _amuthuchippi parpam _aelemental analysis _aEDS analysis
700			_a Raghavi Marimuthu
773	0		_0125265 _9114088 _dMumbai Indian Drugs Manufacturer's Association _tIndian Drugs _x0019-462X
942			_cJA
999			_c133120 _d133120